Arsenal vs Milan
Arsenal will be looking to recover from the shock of a 4-0 defeat to rivals Man Utd in the FA Cup at the weekend with a win at the Emirates with the Champions of Europe, AC Milan. Both sides are after a spot in the next round of the Champions League.
Injuries and Suspensions
Emmanuel Adebayor should start after appearing off the bench against United at the weekend, whilst Manuel Almunia is likely to be left out for Jens Lehmann.
For Milan, Kaka should return and Pato may play, meanwhile Milan's goalkeeping problems are well publicised and veteran goalkeeper Valerio Fiori will play.
Wenger: we are the underdogs
"We are the underdogs by a little bit. They have the experience and won it last year so it is a big challenge against the holders.
"We have the toughest draw of the English teams. This game will define whether or not we can win the trophy.
"If you don't play your best against Milan, you're out."
How they line up
Arsenal: Lehmann - Sagna, Toure, Gallas, Clichy - Eboue, Flamini, Fabregas, Hleb - Adebayor, Eduardo
Milan: Kalac - Oddo, Nesta, Kaladze, Maldini - Gattuso, Pirlo, Ambrosini - Seedorf, Kaka - Pato.