Predicted Manchester United lineup (4-2-3-1) when Cristiano Ronaldo starts

Manchester United return to Premier League action after the international break against Newcastle United.

The Red Devils are likely to hand Cristiano Ronaldo his second debut following his sensational return after 12 years.

It is unclear whether he will make the starting XI. The Portuguese will have just one training session under his belt.

Predicted Line-up:

No changes are expected in the backline from the win at Wolves.

David de Gea has been splendid between the sticks this term.

He made a sublime double save against Wolves before the late Mason Greenwood winner. He will continue in goal.

The defence should pick itself. Aaron Wan-Bissaka and Luke Shaw are automatic choices in the full-back roles.

Raphael Varane should accompany Harry Maguire in central defence, leaving Victor Lindelof on the bench again.

With the arrival of Ronaldo, Greenwood may slot into the right wing with summer signing Jadon Sancho on the other flank.

This should see Paul Pogba continue in his central midfield role. Fred looks set to partner him for the second game running.

Bruno Fernandes is an undisputed pick for the number 10 spot after his exceptional returns over the past 20 months.

Ronaldo is widely expected to lead the attack. We fancy him to start from the off. Edinson Cavani could replace him off the bench.

Predicted Line-up (4-2-3-1): De Gea; Wan-Bissaka, Varane, Maguire, Shaw; Fred, Pogba; Greenwood, Fernandes, Sancho; Ronaldo.